The failed Democratic presidential candidate, who received thousands in campaign funding from Weinstein, told the BBC's Andrew Marr 'we have someone admitting to being a sexual assaulter in the Oval Office.'
She was referring to the Access Hollywood tape leaked during the campaign where Donald Trump was heard boasting about 'grabbing women by the p****y' in 2005.
In fact Trump has not admitted he committed sexual assault and said that he was indulging in 'locker room talk'.
Mrs Clinton is in the UK to promote her hand-wringing book about losing the presidential election.
Hillary Clinton has drawn comparisons between Harvey Weinstein and Donald Trump, saying: 'we have someone admitting to be a sexual assaulter in the Oval Office'
She told Marr: 'I was really shocked and appalled because I've known him through politics as many Democrats have.
'He's been a supporter – he's been a funder for all of us, for Obama, for me, for people who have run for office in the United States.
After all, we have someone admitting to being a sexual assaulter in the Oval Office Hillary Clinton to the BBC's Andrew Marr
'So it was just disgusting and the stories that have come out are heartbreaking.
'And I really commend the women who have been willing to step forward now and tell their stories.
'But I think that it's important that we not just focus on him and whatever consequences flow from these stories about his behavior but that we recognize this kind of behavior cannot be tolerated anywhere, whether it's in entertainment, politics.
'After all, we have someone admitting to being a sexual assaulter in the Oval Office.
'There has to be a recognition that we must stand against this kind of action that is so sexist and misogynistic.'
Clinton compared Donald Trump's Access Hollywood tape to allegations made against Weinstein
And asked about allegations of sexual misconduct levelled at her husband and former president, Bill Clinton, she said: 'That has all been litigated.
'That was subject of a huge investigation in the late 90s and there were conclusions drawn. That was clearly in the past.
'It is something that has to be taken seriously, for anyone not just in entertainment.
'The really sad part of the campaign was how this horrific tape, what he said about women in the past what he said about women during the campaign, was discounted by a lot of voters.'
Harvey Weinstein had his pick of women who were attracted to…
Share this article
The politician, who has previously received campaign funding from Weinstein, called rape and sexual assault allegations facing the movie mogul 'heartbreaking'
Clinton was referring to the Access Hollywood tape leaked during the campaign where Donald Trump was heard boasting about 'grabbing women by the p****y' in 2005
Close relationship: Hillary Clinton benefited from hundreds of thousands from Harvey Weinstein for her campaigns and her family foundation
Clinton was no referring to the Access Hollywood tape leaked during the campaign where Donald Trump was heard boasting about 'grabbing women by the p****y' in 2005
WHAT HARVEY GAVE THE CLINTONS…
$250,000 to the Clinton Foundation
$30,000 to the Hillary Victory Fund
$5,400 to Hillary Clinton's campaign
Unknown millions in donations from friends
…WHAT THE CLINTONS ARE GIVING BACK
$13,000 – and none of the rest so far
Asked if she believed Mr Trump and Weinstein were similar, she said: 'I'm not a psychologist, I can't draw that conclusion. There are credible reports from women about both that sound very similar.'
Weinstein's spokeswoman Sallie Hofmeister has said: 'Any allegations of non-consensual sex are unequivocally denied by Mr Weinstein.'
In another interview with Channel 4, Clinton changed her tune on how she would return cash from Weinstein.
In a CNN interview on Wednesday she said it would be part of her personal giving – which would have given her a tax break.
But on Channel 4, asked if she had returned money from Weinstein, Clinton said it amounted to '12, $16,000 dollars, something like that' and asked if she would give it back said: 'We're going to, yes, we're going to.
'Well it has to come out of our campaign funds, so there's a little more, but it will be done.'
That would mean that Clinton would receive no benefit from the donation.
However it leaves unanswered the other vast amounts of money she and her family have received from and through Weinstein.
As well as personal donations to her campaign, he gave to political action committees linked to the Democratic Party's campaign for her, donated up to $250,000 to the Clinton Foundation, and brought in huge amounts of money from his celebrity circle.
Clinton does not appear to be suggesting she will return a cent of that.
The case against Harvey Weinstein took on an international dimension Thursday, with police in New York and Britain launching investigations – while a fourth woman accused the movie mogul of rape.
An avalanche of claims of sexual harassment, assault and rape by the hugely influential Hollywood producer have surfaced since the publication last week of an explosive New York Times report alleging a history of abusive behavior dating back decades.
Long-term relationship: Gwyneth Paltrow stepped forward to accuse Harvey Weinstein of harassing her. Clinton said she was shocked by the allegations against her friend
On Thursday, American actress Rose McGowan became the fourth woman to accuse Weinstein of raping her
On Thursday, American actress Rose McGowan became the fourth woman to accuse Weinstein of raping her.
A spokesman for the New York Police Department meanwhile confirmed it was investigating a 2004 case, but provided no details.
HARVEY THE DEMS' CASH MACHINE
Here are just some of the donations and fundraising Weinstein was behind according to public records
$679,275 raised as a 'bundler' for Obama's 2012 campaign – one of the top 40 in the country
$250,000 donations to the Democratic National Committee since 2003
$250,000 to the Clinton Foundation since 2003
$30,000 to the Hillary Victory Fund in 2016
$16,200 to Chuck Schumer in total
$5,400 – the legal maximum – to Clinton's campaign in 2016
$5,400 to Richard Blumenthal in 2016
$5,400 to Martin Heinrich in 2017
$5,400 to Al Franken in 2014
$5,000 to Elizabeth Warren in 2012
$10,000 to Corey Booker in 2013
The New York Daily News reported that the case involved aspiring actress Lucia Evans, who earlier told the New Yorker magazine that Weinstein had forced her to perform oral sex on him.
DailyMail.com has already revealed that the FBI have opened an investigation on orders from Trump's Department of Justice.
And a statement from Scotland Yard said the Metropolitan Police were investigating 'an allegation of sexual assault by Merseyside Police.' It did not elaborate.
McGowan also berated Amazon CEO Jeff Bezos in a blistering series of tweets, claiming she told Amazon Studios chief Roy Price that Weinstein had raped her but was ignored.
'Over & over I said it. He said it hadn't been proven. I said I was the proof,' she wrote.
Amazon Studios later said that Price – who has also been accused of sexual harassment by TV producer Isa Hackett – was 'on leave of absence effective immediately.'
On Wednesday, Weinstein was seen in public for the first time in days when paparazzi descended upon him as he left his daughter's home in Los Angeles.
'Guys, I'm not doing OK but I'm trying,' he said in a video obtained by ABC. 'I got to get help. You know what, we all make mistakes.'
As he climbed into an oversized sports utility vehicle, he said he hoped people would give him 'a second chance.'
The TMZ website reported that Weinstein later flew to Arizona to enter a rehabilitation center, possibly The Meadows, a facility northwest of Phoenix where golfer Tiger Woods and supermodel Kate Moss have been treated.